What's it about? Chloe (voice of DREW BARRYMORE), a diamond-clad, bootie wearing Beverly Hills Chihuahua enjoys her luxurious lifestyle so much, she hardly notices Papi (voice of GEORGE LOPEZ), a tough looking Chihuahua who happens to be head-over-paws for the pampered pooch. But when Chloe gets lost in the rough streets of Mexico with only a street-wise German Shepherd (voice of ANDY GARCIA) to help her find her way home, Papi heads south of the border -- joining forces with a motley crew: two humans (PIPER PERABO, MANOLO CARDONA), a sly rat (voice of CHEECH MARIN) and a nervous iguana (voice of PAUL RODRIGUEZ) - to rescue his true love.

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